Clinics in Missouri

Tried multiple antidepressants with little to no relief? You’re not alone. For those with treatment-resistant depression (TRD), FDA-approved options like TMS therapy and Spravato® (Esketamine) offer new hope. This guide explores how these treatments work, who they’re for, and how to find a qualified provider near you with MDDCare.

Struggling with treatment-resistant depression? Spravato® (esketamine) is an FDA-approved nasal spray for those who haven’t found relief with traditional antidepressants. This guide covers how it works, its benefits, potential side effects, and how to find a certified treatment center near you with MDDCare.

Depression can fluctuate—some days may feel manageable, while others feel heavier. If you notice you’re feeling worse or more withdrawn, it may be a sign that you need extra support. Recognizing these changes early can help you take steps toward effective treatment before symptoms become overwhelming.