Clinics in Littleton, Colorado

Depression can fluctuate—some days may feel manageable, while others feel heavier. If you notice you’re feeling worse or more withdrawn, it may be a sign that you need extra support. Recognizing these changes early can help you take steps toward effective treatment before symptoms become overwhelming.

Tried multiple antidepressants with little to no relief? You’re not alone. For those with treatment-resistant depression (TRD), FDA-approved options like TMS therapy and Spravato® (Esketamine) offer new hope. This guide explores how these treatments work, who they’re for, and how to find a qualified provider near you with MDDCare.

Having someone close to you struggle with major depression can be deeply painful and overwhelming, especially when you’re unsure how to help. While you can’t “fix” their depression, your support can play a meaningful role in their healing. This article explores ways you can be there for them during this difficult time.