Know different types of depressions

Knowing the right terms and difference can guide people toward the best care in case of mental health. We want to make it easy for patients to find the right solution by helping them understand the distinctions between Major Depressive Disorder (MDD), Clinical Depression, and Treatment-Resistant Depression (TRD) without being too technical about it.
Each type of depression reflects a specific experience, and knowing the difference ensures the right care is provided at the right time:

Major Depressive Disorder (MDD)
MDD is more than sadness or a tough day. It’s a serious mood disorder that impacts someone’s ability to enjoy life or function normally. It can last for weeks, months, or even years and causes:

  • Loss of energy and motivation
  • Sleep disturbances
  • Appetite changes
  • Trouble maintaining relationships

When someone has MDD, your favorite activities feel pointless, and hope seems out of reach. MDD requires more than encouragement, it needs proper treatment to guide the patient toward recovery.

Clinical depression
Clinical depression is a broad term used to describe all forms of depression that need professional care, including MDD. However, not all cases look the same.

  • Some patients experience episodic depression, it comes and goes
  • Others live with chronic symptoms that never fully go away

Clinical depression reflects the complexity of the condition, which means it takes time and care to diagnose and treat effectively. But the message is simple: No one needs to go through it alone. Help is always available.

Treatment-Resistant Depression (TRD)
TRD occurs when someone has tried two or more antidepressants or other standard treatments without success. It can be incredibly frustrating for patients and caregivers, making people feel stuck. But there is hope.

Newer treatments like TMS and Spravato offer promising results for those with TRD. This is a reminder that healing isn’t always linear—exploring new therapies can open the door to better outcomes.

You Don’t Have to Face Depression Alone
Major Depressive Disorder is treatable, even when it feels overwhelming. Hope and healing are within reach—the right care can make all the difference.

Take the first step today.
Find a specialist near you offering innovative treatments like TMS and Spravato. You deserve to feel better.

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About the Author

Julia Kelly

Analyst at MDDCare

Julia is a passionate mental health advocate and content specialist at MDDCare. With a deep commitment to raising awareness about modern mental health treatments, Julia provides expert insights and informative resources to help guide individuals on their journey to wellness.