When it comes to mental health, knowing the right terms can guide people toward the best care. At MDD Care, we want to make it easy for patients to find the right solution by helping them understand the distinctions between Major Depressive Disorder (MDD), Clinical Depression, and Treatment-Resistant Depression (TRD). Each label reflects a specific experience, and knowing the difference ensures the right care is provided at the right time.
Major Depressive Disorder is treatable, even when it feels overwhelming. Hope and healing are within reach—the right care can make all the difference.
Transcranial Magnetic Stimulation (TMS)
This is a non-invasive procedure that uses magnetic fields to stimulate nerve cells in the brain, particularly targeting areas involved in mood regulation. It is primarily used for people with MDD who have not responded to other treatments.
TMS utilizes an electromagnetic coil lightly placed against the patient’s head to generate magnetic pulses, targeting localized neurons in the brain, specifically those involved in mood regulation. This non-invasive technique enhances neuronal excitability, contributing to neuroplastic changes recognized for their role in alleviating depressive symptoms.
Esketamine (Spravato)
This is a derivative of ketamine, is a novel treatment for treatment-resistant depression. Unlike traditional antidepressants that target serotonin, norepinephrine, or dopamine, esketamine works on the glutamate system, which is believed to play a key role in mood regulation and neuroplasticity.
As a derivative of ketamine, Spravato functions primarily as an NMDA receptor antagonist, facilitating rapid increases in synaptic transmission and neurotrophic factor release, which are crucial for mood regulation and cognitive function.
Understand the Key Differences in Depression Types
When it comes to mental health, knowing the right terms can guide people toward the best care. At MDD Care, we want to make it easy for patients to find the right solution by helping them understand the distinctions between Major Depressive Disorder (MDD), Clinical Depression, and Treatment-Resistant Depression (TRD). Each label reflects a specific experience, and knowing the difference ensures the right care is provided at the right time.
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Frequently Asked Questions
Some frequently asked questions about Major Depressive Disorder (MDD). These responses provide insights into symptoms, treatment options, and ways to manage the condition effectively.
What is Major Depressive Disorder (MDD), and what are its symptoms?
MDD is a mental health condition that affects how you feel, think, and behave. It causes persistent sadness, loss of interest in activities, and other emotional and physical symptoms.
Common symptoms include:
- Persistent sadness or low mood
- Loss of interest in activities you once enjoyed
- Changes in appetite or weight
- Trouble sleeping or sleeping too much
- Fatigue or lack of energy
- Feelings of guilt or worthlessness
- Difficulty concentrating
- Thoughts of death or suicide
Can MDD be prevented?
There’s no guaranteed way to prevent MDD, but managing stress, building supportive relationships, and seeking help early can reduce the risk or severity of future episodes.
Can MDD affect physical health?
Yes. MDD can cause physical symptoms like fatigue, headaches, and changes in appetite. It also increases the risk of chronic conditions, such as heart disease and diabetes.
How long does MDD last?
The length varies—some people experience a single episode, while others have recurrent depression. With treatment, symptoms can improve within a few weeks to months.
How is MDD diagnosed?
A healthcare provider diagnoses MDD by evaluating your symptoms, how long you’ve had them, and how they impact your daily life. They may also use standardized tools like the PHQ-9 questionnaire.
What causes MDD?
The exact cause is unknown, but it may involve a combination of genetics, brain chemistry, stress, trauma, or environmental factors.