Relief from Depression Starts Here

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These clinics specialize in treating depression, especially for patients who haven’t found success with traditional antidepressant medications alone.

    Spravato® (Esketamine)

    Spravato® (Esketamine) for Treatment-Resistant Depression

    SPRAVATO® offers a different approach and is the only nasal spray treatment indicated for treatment-resistant depression (TRD)

    How Spravato® Works

    Spravato is a nasal spray that contains esketamine, a potent form of ketamine. Ketamine has been used for years as an anesthetic, and recent studies have shown it has powerful antidepressant effects. By targeting the NMDA receptors Spravato helps restore the balance of brain chemicals and can deliver fast relief for patients with TRD.

    Spravato is administered in a supervised medical setting to ensure safety. Typically, patients will receive their first few doses at a clinic, where medical staff can monitor them for side effects.

    If you or someone you know is struggling with treatment-resistant depression, Spravato could be the breakthrough treatment you've been looking for.

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    74% Patients

    Reported significant symptom improvement after completing Spravato treatment.

    Source: Esketamine Clinical Trial, 2019
    25% Patients

    Achieved full remission from their depression symptoms after 4 weeks of treatment.

    Source: Esketamine for TRD—New England Journal of Medicine, 2019
    24 Hours

    Many patients experience symptom relief within 24 hours after the first dose.

    Source: Clinical Use of Esketamine—American Journal of Psychiatry, 2020

    Ask the Experts

    Watch this video on the SPRAVATO® Important Safety Information

    Watch this video on the SPRAVATO® Important Safety Information

    What are the benefits?

    Spravato (esketamine) is a prescription nasal spray that can help treat adults with treatment-resistant depression (TRD). Some benefits of Spravato include:

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    Rapid relief

    Spravato can provide relief from depression symptoms within hours or days, which is much faster than traditional antidepressants. This fast response can be especially beneficial for individuals who need quicker relief from severe depressive episodes.

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    Reduced risk of relapse

    Spravato can help reduces instances of depression relapse. By following consistent treatment schedule, it can help stabilize mood and provide ongoing support for long-term mental health.

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    Improved mood

    Spravato can help patient improve mood and overall sense of well-being, it brings a positivity in thought process. Regular use has been shown to lead to more sustained improvements in emotional state and quality of life.

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    Personalized dosing

    The dosage of Spravato can be customized to each individual's needs. Such flexibility of dosages allows healthcare providers to adjust the treatment based on how a person responds, ensuring optimal results.

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    In-clinic administration

    Spravato is administered in a supervised healthcare setting with a session of not more than an hour. This ensures proper monitoring for safety and efficacy, providing peace of mind during treatment.

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    Modulates glutamate activity

    Spravato can help restore balance to neural circuits affected by depression. By modulating glutamate activity, it targets the brain’s neurotransmitter system to improve mood and cognitive function.

    Patient Testimonials

    Stories of people just like you.

    Nicole’ Story

    There were days where I would just break down crying in my bathroom because I just couldn’t do it. I couldn’t get up. I couldn’t take a shower. I couldn’t physically do anything.

    - Nicole, Spravato Patient

    Ben’ Story

    This internal voice wants to convince me that I’m a terrible person, that I don’t know what I’m doing, that nobody likes me, that I’m a literal piece of garbage who doesn’t deserve anything.

    - Ben, Spravato Patient

    Amelia’ Story

    I felt like the depression just robbed me of, of everything. I mean, it almost robbed me of my life.

    - Amelia, Spravato Patient

    Grace’ Story

    So I didn’t notice right away but my family did. My mom would say that she would see me smiling more. Or my boyfriend would say that he had heard me laugh for the first time in far too long.

    - Grace, Spravato Patient

    Sally’ Story

    Now, my husband and I love to go see live music. We like to cook. We like to be anywhere near water, really. I have learned that’s part of how I manage my depression, making sure I get outside.

    - Sally, Spravato Patient
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